Combinatorial targeting of cancer bone metastasis using mRNA engineered stem cells.
Segaliny AI, Cheng JL, Farhoodi HP, Toledano M, Yu CC, Tierra B, Hildebrand L, Liu L, Liao MJ, Cho J, Liu D, Sun L, Gulsen G, Su MY, Sah RL, Zhao W.
Segaliny AI, et al.
EBioMedicine. 2019 Jul;45:39-57. doi: 10.1016/j.ebiom.2019.06.047. Epub 2019 Jul 4.
EBioMedicine. 2019.
PMID: 31281099
Free PMC article.
INTERPRETATION: Our combinatorial targeting of both the cancer cells and the niche represents a simple, safe and effective way to treat metastatic bone diseases, otherwise difficult to manage with existing strategies. It can also be applied to other cell types (e.g., T cel …
INTERPRETATION: Our combinatorial targeting of both the cancer cells and the niche represents a simple, safe and effective way to treat meta …